Jardiance, or generic name empagliflozin, is a prescription drug used mainly for the treatment of type 2 diabetes. It works by making the kidneys excrete glucose from the body through urine, which lowers blood sugar levels. Although controlling blood sugar is Jardiance's main purpose, certain reports and research indicate that Jardiance may also help some people lose weight.
Knowing Jardiance:
It's important to comprehend how this drug functions before exploring any possible effects on weight. Jardiance is a member of the SGLT2 inhibitor medication class. These drugs work by preventing the kidneys' sodium-glucose cotransporter 2 (SGLT2). They reduce blood sugar levels by encouraging the excretion of glucose in the urine by doing this.
The Link to Reduction of Body Weight:
Although losing weight is not one of Jardiance's main intended effects, some patients may experience it as a side effect of taking the drug. There are a lot of reasons why this might take place.
Caloric Loss by Glucose Excretion:
Jardiance acts by causing the body to eliminate glucose through the kidneys. Given that glucose is a caloric substance, this mechanism efficiently causes calorie loss and may aid in weight loss.
Diuresis:
Jardiance and other SGLT2 inhibitors cause diuresis, or increased urination, as one of their side effects. Some people may lose water weight as a result of this, especially in the early phases of treatment.
Diminished Fat Mass:
According to certain research, SGLT2 inhibitors may eventually cause a decrease in fat mass. Although the precise mechanism underlying this remains unclear, it may have to do with modifications in metabolism or other physiological processes that the medicine affects.
Clinical Support:
Numerous clinical investigations have examined Jardiance's possible effect on weight. A prominent 2015 study that looked at the impact of empagliflozin (Jardiance) on body weight and other metabolic parameters in people with type 2 diabetes was published in The Lancet Diabetes & Endocrinology. According to the study, participants getting empagliflozin significantly lost body weight in comparison to those receiving a placebo.
Similarly, in 2019 the Journal of Clinical Medicine published a systematic review and meta-analysis.
Caveats and Considerations: Although some people may lose weight while using Jardiance, it's important to approach this possible advantage cautiously and be aware of the following factors:
Personal Differences:
People using Jardiance may have varying degrees of weight loss. Not everyone will lose a lot of weight, and each person's reaction to the drug may be different.
Additional Elements
Jardiance users' weight loss may be attributed to a number of variables, such as their diet, level of exercise, use of other drugs, and underlying medical issues. When assessing Jardiance's effects on weight, it's critical to take into account the larger context of a person's lifestyle and medical background.
Safety and Monitoring:
Although losing weight can be a desired result for some people, it's important to make sure that any weight changes take place within a range that is safe and healthy. Healthcare professionals should routinely check on patients taking Jardiance to determine weight as well as other metabolic indicators and any drug adverse effects.
Outcome
In conclusion, although it is not the main reason to use Jardiance, some people may benefit from weight loss as a side effect of the medication. Some individuals may lose weight as a result of the medication's mechanism of action, which includes encouraging glucose excretion and causing diuresis. But each person's weight loss journey and its consequences are unique, so it's crucial to
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